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Tomorrow's health is... Defining a new possible.

Lead Project Manager

Irving, Texas, Alpharetta, Georgia, Columbus, Ohio Job ID JR0157276 Category General Project Management, Business & Strategy Post Date Nov. 10, 2026
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McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.

Lead Project Manager (P5)

We are looking for a Lead Project Manager seated within Enterprise Performance & Transformation to support transformation initiatives. The candidate will be responsible for leading complex programs and initiatives that deliver significant financial, operational, and customer and employee satisfaction impacts. 

You will be the strategic partner to the leadership team within a given initiative enabling and overseeing the end-to-end delivery of multiple projects through all phases from initiation to completion. A deep understanding of all corporate finance functions and experience implementing financial applications is highly desired.

The selected candidate will support complex projects as a program lead, coordinating work across multiple workstreams, cooperating with the business stakeholders to ensure alignment, and collaborating to ensure a comprehensive solution that meets requirements and expectations.  Additionally, the role will coach and mentor project managers across the team and act as an informal leader.

The position reports to the Director of Project Management within Business Enablement.  

Project Execution

  • Lead the planning, execution and successful delivery of highly complex projects across the transformation portfolio such as technology implementations, automations, and process re-designs.
  • Ensure adherence to project goals, timelines and budget – primarily supporting the business in remaining focused on high priority capabilities and managing scope-creep with a rigorous strategic approach.
  • Coordinate and manage multiple vendors and stakeholders to ensure on-time delivery, within budget and in accordance with agreed upon quality standards.
  • Prepare regular project status reports, deliver progress updates to stakeholders, lead SteerCo meetings and maintain project documentation and artifacts as needed.
  • Manage project budgets, track expenditures and ensure cost-effectiveness throughout the project lifecycle by leading the business towards effective prioritization.
  • Identify and mitigate project risks, proactively addressing issues that may impact project success.
  • Identify opportunities for process improvement and best practices, driving efficiency and effectiveness in project delivery.
  • Foster strong cross-functional collaboration and working relationships with various teams and stakeholders to ensure successful project outcomes.

Consultation Skills

  • Keen awareness of the goals and objectives of a program and their connection to overall strategy.
  • Engage with executive and leadership stakeholders to gain support, influence decision-making and ensure project alignment with organizational priorities.
  • Build strong relationships with the relevant functional leadership and building in-depth knowledge of the strategic priorities for each functional and understand how they operate.
  • Ability to absorb and process large quantities of disparate information, synthesize quickly and connect dots across workstreams where appropriate
  • Support business case development with input from all relevant stakeholders and support the business to present to leadership team for approval.
  • Strong interpersonal and consulting skills – ability to assess needs, collaborate and deliver practical solutions that drive results; an excellent listener that seeks to understand multiple viewpoints; effective at influencing, facilitating, and problem solving
  • Build strong and trusting relationships across multiple teams and departments and collaborate with business leaders to execute plans

Change Leadership

  • Champion for change to ensure adoption of solutions across the organization
  • Acting a change lead, if one is not assigned on the program

Desired Skills

  • Experience as a project manager over large, complex, and Enterprise-wide technology implementations
  • Expert level Project Management understanding and strong financial business acumen
  • Demonstrated ability to motivate, influence and gain commitment at all levels of the organization
  • Ability to understand and identify the connections and dependencies between specific projects and the key strategic objectives
  • Ability to think through, organize and assist with leading multiple projects and tasks concurrently
  • Ability to facilitate and communicate effectively in a hybrid environment
  • Expert Verbal/written communication skills in English

Additional Skills

  • Experience supporting matrixed teams and experience supporting projects across functional boundaries
  • Demonstrated ability to influence with limited authority
  • Resourceful with an innovative and entrepreneurial mindset

Degree, certification and experience:

  • Degree or equivalent and typically requires 10+ years of relevant experience.
  • Lean/Six Sigma certification (Black Belt) and/or Project Management Institute (PMP) certification is a plus.

Employee Benefits

  • Inclusive work environment
  • Hybrid work model
  • Flexible full-time schedule
  • Comprehensive benefits (including health and dental insurance, retirement savings plans, etc.)
  • Wellness programs
  • Professional development opportunities
  • Employee resource groups
  • Employee assistance programs
  • Tuition reimbursement
  • Employee discounts on products and services

These benefits are designed to support the well-being and success of McKesson employees, ensuring they have access to the resources and support they need to thrive in their careers and personal lives.


Why McKesson 


At McKesson, we foster an inclusive, flexible, and growth‑oriented environment designed to help our people thrive. 

  • Hybrid work model with a flexible full‑time schedule 
  • Comprehensive health, dental, and retirement benefits 
  • Wellness and employee assistance programs 
  • Professional development and tuition reimbursement 
  • Employee resource groups and community engagement opportunities 
  • Employee discounts on products and services 

These benefits are designed to support your well‑being and success—professionally and personally—so you can bring your best self to work and help advance health outcomes for all.

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please click here.

Our Base Pay Range for this position

$140,200 - $233,600

McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:

McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.


McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.

McKesson job postings are posted on our career site: careers.mckesson.com.

McKesson is an Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. For additional information on McKesson’s full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page.

McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment, please contact us by sending an email to (United States) Disability_Accommodation@McKesson.com or (Canada) Accessibility@mckesson.ca. Resumes or CVs submitted to this email box will not be accepted.

Join us at McKesson!

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McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:

  • McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.
  • McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.
  • McKesson job postings are posted on our career site: careers.mckesson.com

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