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Tomorrow's health is... Defining a new possible.

Senior Manager, Change Management & Transformation

Nashville, Tennessee Job ID JR0140995 Category General Project Management, Business & Strategy Post Date Jan. 09, 2026
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It’s More Than a Career, It’s a Mission.


Our people are the foundation of our success. By joining our growing team at Sarah Cannon Research Institute (SCRI), a subsidiary of McKesson, you will have the opportunity to become part of one of the largest community-based cancer programs to advance oncology treatments and improve outcomes for cancer patients across the globe. We look for mission-driven candidates who have a desire to advance the fight against cancer and make a difference in the lives of patients diagnosed with cancer every day.

Our Mission


People who live with cancer – those who work to prevent it, fight it, and survive it – are at the heart of every decision we make. Bringing the most innovative medical minds together with the most passionate caregivers in their communities, we are transforming care and personalizing treatment. Through clinical excellence and cutting-edge research, SCRI is redefining cancer care around the world.

The Senior Manager, Change Management &Transformationis responsible fordesigning, leading, and operationalizing enterprise-wide change initiatives at SCRI. This role serves as a senior change leader, partnering closely with executive sponsors, operational leaders, and transformation teams to ensure strategic initiatives are successfully adopted, sustained, and embedded into how the organization works.

This role leads and coaches a team of changemanagersproviding strategic oversight across large-scale, complex initiatives with significant people and organizational impact. The Senior Manager applies structured change management methodologies, advanced stakeholder engagement techniques, and data-driven adoption strategies to improve business outcomes, employee experience, and organizational readiness. Success in this role requires deepexpertisein change management, strong influencing skills, and the ability to lead across a highly matrixed clinical and research environment.

Duties include but are not limited to:

  • Lead the change strategy for high-impact, enterprise-wide initiatives, ensuring alignment to SCRI’s strategic priorities and operating model.

  • Serve as the primary change advisor to executive sponsors and senior leaders, guiding them through complex organizational, behavioral, and cultural change.

  • Design and oversee comprehensive change management plans, including stakeholder analysis, impact assessments, communication strategies, training approaches, readiness measures, and sustainment plans.

  • Ensure change strategies are proactively integrated into project and program delivery—not treated as downstream activities.

  • Build strong, trust-based partnerships with senior leaders, enabling them to visibly and effectively sponsor change.

  • Setenterprise direction forchangecommunications across strategic initiatives and organizational transformations, ensuring clarity, consistency, and alignment with SCRI priorities. 

  • Ownthe communication strategy for complex programs and organizational changes, including executive messaging, enterprise updates, and readiness communications. 

  • Adviseand partner with executive sponsors and senior leaders on messaging, sequencing, and escalation related tohigh‑impactchange initiatives. 

  • Ensuretimelyescalation of material risks, adoption challenges, and change impacts to internal leadership and external partners, enabling informeddecision‑making. 

  • Providegovernance and oversight forchangecommunications delivered by program teams, ensuring quality, consistency, and effectiveness across the portfolio. 

  • Aligninternal and external partner communications to support successful delivery, adoption, and sustainment of enterprise initiatives. 

  • Establishmechanisms to assess message effectiveness and stakeholder sentiment, using insights to refine communication strategies and reinforce adoption.

  • Prepare leaders to lead change through targeted coaching, messaging, and engagement strategies.

  • Directly manage and mentor Program ManagersandChange Managers, setting clear expectationsfor changeexcellence.

  • Build enterprise change capability by coaching teams, introducing standardized change frameworks, tools, and best practices, and fostering a culture of adoption-focused delivery.

  • Partner with theDirectorof Strategy & Transformation to support prioritization and sequencing of initiatives from achangecapacity and readiness perspective.

  • Maintain awareness of cumulative change impacts across the organization and recommend mitigation strategies to reduce change fatigue and risk.

  • Define and track adoption, readiness, and sustainment metrics to assess change effectiveness and inform course corrections.

  • Ensure implemented changes are reinforced through governance, performance measures, and operational ownershippost‑implementation.

  • Identifyopportunities to improve SCRI’s changemanagementmaturity, tools, and governance.

  • Propose and implement enhancements that improve how the organization absorbs and sustains change over time.

Mandatory:The following are mandatory expectations of all SCRIemployees.

  • Practices and adheres to the “Code of Conduct” philosophy and “Mission and Value Statement.”

  • During your employment with SCRI,you willbe routinelyassigned training requirements. You are expected to complete any training assignments by the due date.


Knowledge: A body of information needed to perform tasks; May be obtained through education, training or experience.

  • Change management and project management techniques and tools

  • Knowledgeable and experienced in the research environment and healthcare processes.

  • Strong workingrelationshipwith leadership whichallowsfor quick problem resolution and staffsupport.

  • Experience leadingenterprise widestrategicinitiativeswithlarge changeimpacts.


Skills: The proficiency to perform a certain task.

  • Senior-level facilitation, influencing, and executive communication skills 

  • Stakeholderengagement and conflict navigation across diverse audiences 

  • Coachingand people leadership skills, including developing change practitioners 

  • Data-informeddecision-makingusing adoption and readiness metrics 

  • Strongwritten and verbal communication skills; ability to translate complexity into clear, compelling messages


Abilities: An underlying, enduring trait useful for performing duties.

  • Abilityto quicklyestablishcredibility with executives and frontline leaders 

  • Abilityto lead through ambiguity and resistance whilemaintainingalignment and momentum 

  • Abilityto balance multiple concurrent changes and advise on organizational change capacity 

  • Comfortchallenging assumptions and raising risks constructively at all levels 

  • Abilitytooperateeffectively within a highly matrixed organization


Minimum Qualifications:

  • Master’s Degree required

  • 7+ years of experience in program management

  • 2+ years of experience in people management

  • Experience leading enterprise‑wide strategic initiatives with significant organizational change impacts

  • Prosci Change Management Certification or equivalent required

  • Six Sigma Green Belt or Black Belt highly preferred

This role is hybrid in Nashville, TN.

About Sarah Cannon Research Institute


Sarah Cannon Research Institute (SCRI) is one of the world’s leading oncology research organizations conducting community-based clinical trials. Focused on advancing therapies for patients over the last three decades, SCRI is a leader in drug development. In 2022, SCRI formed a joint venture with former US Oncology Research to expand clinical trial access across the country. It has conducted more than 850 first-in-human clinical trials since its inception and contributed to pivotal research that has led to the majority of new cancer therapies approved by the FDA in the past decade. SCRI’s research network brings together more than 1,300 physicians who are enrolling patients into clinical trials at more than 200 locations in 20+ states across the U.S. Please click here to learn more about our research offerings.

We care about the well-being of the patients and communities we serve, and that starts with caring for our people. That’s why we have a Total Rewards package that includes comprehensive benefits to support physical, mental, and financial well-being. Our Total Rewards offerings serve the different needs of our diverse colleague population and ensure they are the healthiest versions of themselves. For more information regarding benefits through our parent company, McKesson, please click here.

As part of Total Rewards, we are proud to offer a competitive compensation package. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered.

McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:

McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.


McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.

McKesson job postings are posted on our career site: careers.mckesson.com.

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:

  • McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.
  • McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.
  • McKesson job postings are posted on our career site: careers.mckesson.com.

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