Sr. Finance Manager
Irving, Texas Job ID JR0146096 Category FP&A, Accounting & Finance Post Date Apr. 22, 2026McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.
What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.
Position Summary
The Sr. Manager, Cell & Gene Therapy Financial Performance plays a critical role within US Oncology Network (USON) Finance by serving as the subject matter expert for the financial performance of Cell & Gene therapies across the network. This position is accountable for developing the financial performance framework for Cell & Gene—including definitions, measurement methodology, and executive-ready reporting—while partnering closely with practices and cross-functional stakeholders to ensure performance is understood, accurate, and actionable.
This role translates complex, evolving therapy economics into clear financial insights for executive leadership. It leads modeling and scenario analysis across key drivers (utilization, site-of-care dynamics, acquisition and reimbursement, program costs, and timing impacts), and it establishes repeatable reporting that supports decision-making, performance improvement, and strategic planning.
Operating at the intersection of finance, operations, and strategy, the Sr. Manager drives continuous improvement in data quality, analytical tools, and governance for Cell & Gene financial performance. By maintaining disciplined, transparent analytics and communicating results with executive presence, this role supports USON’s mission and enables sound financial stewardship as these therapies scale.
Key Responsibilities
Serve as the finance subject matter expert for Cell & Gene Therapy performance across USON, owning the end-to-end performance measurement approach (definitions, key metrics, methodology, and controls).
Establish standardized performance views and interpretation guidelines to ensure consistent understanding across practices and stakeholders.
Lead development and refinement of financial models that explain and forecast Cell & Gene performance, focusing on transparency, accuracy, and decision usefulness.
Practice & Stakeholder Partnership / Performance Determination
Partner directly with practices and key stakeholders (FP&A, Finance Ops, Revenue Cycle, Managed Care, operations/clinical partners as applicable) to determine and validate Cell & Gene financial performance.
Investigate performance drivers and variances, ensuring results are well-supported, reconciled, and communicated in business terms.
Translate practice-specific realities into consistent network-level reporting and comparable performance narratives.
Executive Reporting & Decision Support
Deliver concise, executive-ready reporting packages, including performance commentary, variance explanations, and forward-looking outlooks.
Present findings and recommendations with strong executive presence, tailoring content for senior leadership decision-making.
Build “so what” insight: clarify risks, opportunities, and key actions based on the financial performance signals.
Modeling, Scenario Planning & Forecasting
Develop scenario models (volume, timing, reimbursement sensitivity, program cost structures) to support budgeting/forecasting and strategic planning for Cell & Gene growth.
Create driver-based views that allow leadership to understand what is changing, why, and what levers exist.
Support annual planning cycles and in-year updates with disciplined assumptions and documented logic.
Data, Reporting Automation & Visualization
Build and enhance repeatable reporting and dashboards (Excel and/or Power BI) that provide timely, accurate Cell & Gene financial performance visibility.
Improve efficiency through automation and standardized data pipelines, while maintaining strong data governance and controls.
Ensure reporting is consistent, auditable, and easy for business partners to consume.
Strategic Initiatives, Governance & Continuous Improvement
Lead or contribute to strategic initiatives related to Cell & Gene financial performance measurement, process improvement, and analytics maturity.
Establish governance routines (documentation, metric definitions, refresh cadence, stakeholder alignment) to support scaling and sustainability.
Identify emerging needs and proactively recommend enhancements to tools, processes, and performance management.
Minimum Requirement
- Degree or equivalent and typically requires 10+ years of relevant experience. Less years required if has relevant Master’s or Doctorate qualifications.
Education
- Bachelor’s degree required; advanced degree (MBA, MS, or similar) in finance, analytics, or related field preferred.
Critical Skills
- 10+ years of progressive experience in FP&A, financial modeling, or analytics, with a demonstrated track record of leading complex forecasting and budgeting initiatives in a large, matrixed organization.
- Deep expertise in advanced analytics, statistical modeling, and AI/ML applications for forecasting. Mastery of Excel, Power BI/Tableau, and financial systems (e.g., SAP, Oracle, Hyperion).
- Recognized as an in-house expert and lead contributor; experience mentoring others and leading large-scale projects.
Prior FP&A experience performing budget, forecast, plan, variance analyses
Excellent financial modeling and problem-solving skills
Intermediate skills in Excel (formulas, modeling, pivot tables) and PowerPoint
Financial systems experience with ability to reconcile information from multiple sources
Additional Knowledge & Skills
Strong internal and external customer service and relationship-building skills
Executive presence and experience with presentations to various leadership levels
Ability to provide strategic recommendations and influence stakeholders to make decisions
Excellent project management skills
Intellectual curiosity & highly independent
Motivated self-starter that is well organized, dependable, efficient and results-oriented
Strong time management and organization skills with flexibility to work in a fast-paced and changing work environment
Experience collaborating with C-suite executives
Ability to collaborate with teams across multiple functions to affect a solution
Prior leadership experience a plus
This role is a hybrid position. The selected candidate is expected to work on-site at our Las Colinas office a minimum of two (2) days per week, with the remaining days worked remotely. Specific in-office days may be designated based on team needs and business priorities.
We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please click here.
Our Base Pay Range for this position
$127,200 - $212,000McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:
McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.
McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.
McKesson job postings are posted on our career site: careers.mckesson.com.
McKesson is an Equal Opportunity Employer
McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. For additional information on McKesson’s full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page.
McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment, please contact us by sending an email to (United States) Disability_Accommodation@McKesson.com or (Canada) Accessibility@mckesson.ca. Resumes or CVs submitted to this email box will not be accepted.
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McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:
- McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.
- McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.
- McKesson job postings are posted on our career site: careers.mckesson.com.
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